1. Yoshii D, Nakagawa T, Komohara Y, Kawaguchi H, Yamada S, Tanimoto A.
Phenotypic Changes in Macrophage Activation in a Model of Nonalcoholic Fatty Liver Disease using Microminipigs.
J Atheroscler Thromb 28: 444-451, 2021.

2. Saku T, Takashio S, Tsuruta Y, Otsuka Y, Takae M, Kiyama T, Yamamoto E, Kaikita K, Hotta T, Matsumoto S, Kang D, Tsujita K, Komohara Y.
Comparison of electron microscopic findings and clinical presentation in three patients with mitochondrial cardiomyopathy caused by the mitochondrial DNA mutation m.3243A > G.
Med Mol Morphol 54: 181-186, 2021.

3. Kanemitsu K, Iwatsuki M, Yamashita K, Komohara Y, Morinaga T, Iwagami S, Eto K, Nagai Y, Kurashige J, Baba Y, Yoshida N, Baba H.
Two Asian families with gastric adenocarcinoma and proximal polyposis of the stomach successfully treated via laparoscopic total gastrectomy.
Clin J Gastroenterol 14: 92-97, 2021.

4. Liu Y, Baba Y, Ishimoto T, Tsutsuki H, Zhang T, Nomoto D, Okadome K, Yamamura K, Harada K, Eto K, Hiyoshi Y, Iwatsuki M, Nagai Y, Iwagami S, Miyamoto Y, Yoshida N, Komohara Y, Ohmuraya M, Wang X, Ajani JA, Sawa T, Baba H.
Fusobacterium nucleatum confers chemoresistance by modulating autophagy in oesophageal squamous cell carcinoma.
Br J Cancer 124: 963-974, 2021.

5. Kusunoki M, Fujiwara Y, Komohara Y, Imamura Y, Honda R, Ohba T, Katabuchi H.
Hemoglobin-induced continuous activation of macrophages in endometriotic cysts: a potential mechanism of endometriosis development and carcinogenesis.
Med Mol Morphol 54: 122-132, 2021.

6. Nomoto D, Baba Y, Okadome K, Yagi T, Kalikawe R, Kiyozumi Y, Harada K, Eto K, Hiyoshi Y, Nagai Y, Ishimoto T, Iwatsuki M, Iwagami S, Miyamoto Y, Yoshida N, Komohara Y, Watanabe M, Baba H.
Prognostic impact of PD-1 on tumor infiltrating lymphocytes in 433 resected esophageal cancers.
Ann Thorac Surg, in press.

7. Sakamoto R, Kajihara I, Mijiddorj T, Otsuka-Maeda S, Sawamura S, Nishimura Y, Kanemaru H, Kanazawa-Yamada S, Nakamura K, Honda N, Makino K, Aoi J, Igata T, Makino T, Masuguchi S, Fukushima S, Morinaga J, Komohara Y, Ihn H.
Existence of Staphylococcus aureus correlates with the progression of extramammary Paget's disease: potential involvement of interleukin-17 and M2-like macrophage polarization.
Eur J Dermatol 31: 48-54, 2021.

8. Morimoto Y, Ono S, Yoshida S, Mishima H, Kinoshita A, Tanaka T, Komohara Y, Kurotaki N, Kishino T, Okazaki Y, Ozawa H, Yoshiura KI, Imamura A.
A unique missense variant in the E1A-binding protein P400 gene is implicated in schizophrenia by whole-exome sequencing and mutant mouse models.
Transl Psychiatry 11: 132, 2021.

9. Maeshiro M, Shinriki S, Liu R, Nakachi Y, Komohara Y, Fujiwara Y, Ohtsubo K, Yoshida R, Iwamoto K, Nakayama H, Matsui H.
Colonization of distant organs by tumor cells generating circulating homotypic clusters adaptive to fluid shear stress.
Sci Rep 11: 6150, 2021.

10. Kumamoto K, Tasaki T, Ohnishi K, Shibata M, Shimajiri S, Harada M, Komohara Y, Nakayama T.
CD169 Expression on Lymph Node Macrophages Predicts in Patients With Gastric Cancer.
Front Oncol 11:636751, 2021.

11. Fujiwara Y, Maeda R, Takeshita H, Komohara Y.
Alginates as food ingredients absorb extra salt in sodium chloride-treated mice.
Heliyon 7: e06551, 2021.

12. Komohara Y, Miyamura T, Miyashita A, Shigeta H, Nakagawa T, Fukushima S.
An Autopsy Case of Metastatic Melanoma Originating from the Nasal Cavity That Was Treated With Nivolumab and Ipilimumab.
Cancer Diagnosis and Prognosis 1: 7-12, 2021.

13. Tsukamoto H, Komohara Y, Oshiumi H.
The role of macrophages in anti-tumor immune responses: pathological significance and potential as therapeutic targets.
Hum Cell 34: 1031-1039, 2021.

14. Yamamura K, Beppu T, Oda E, Sato N, Yuki H, Motohara T, Miyamoto H, Miyamura S, Onishi K, Komohara Y, Akahoshi S.
Hepatic Inflammatory Pseudotumor Mimicking Malignant Tumor With Rare Onset of Intra-abdominal Hemorrhage.
Anticancer Res 41: 2727-2732, 2021.

15. Sato M, Kadomatsu T, Miyata K, Warren JS, Tian Z, Zhu S, Horiguchi H, Makaju A, Bakhtina A, Morinaga J, Sugizaki T, Hirashima K, Yoshinobu K, Imasaka M, Araki M, Komohara Y, Wakayama T, Nakagawa S, Franklin S, Node K, Araki K, Oike Y.
The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis.
Nat Commun 12: 2529, 2021.

16. Miura Y, Anami T, Yatsuda J, Motoshima T, Oka S, Suyama K, Inoshita N, Kinowaki K, Urakami S, Kamba T, Komohara Y.
HLA-DR and CD74 Expression and the Immune Microenvironment in Renal Cell Carcinoma.
Anticancer Res, 41: 2841-2848, 2021.

17. Nohara T, Fujiwara Y, El-Aasr M, Ikeda T, Ono M, Nakano D, Kinjo J.
Thiolane-type sulfides from garlic, onion, and Welsh onion.
J Nat Med 75: 741-751, 2021.

18. Anami T, Komohara Y, Miura Y, Yamanaka K, Kurahashi R, Segawa T, Motoshima T, Murakami Y, Yatsuda J, Yamaguchi T, Sugiyama Y, Jinnouchi Y, Kamba T.
High T-cell infiltration in tumor tissue and younger age predict the response to pembrolizumab in recurrent urothelial cancer.
Med Mol Morpho, in press.

19. Harada M, Iida Y, Kotani H, Minami T, Komohara Y, Eto M, Yoshikawa K, Uemura H.
T-cell responses and combined immunotherapy against human carbonic anhydrase 9-expressing mouse renal cell carcinoma.
Cancer Immunol Immunother, in press.

20. Matsusaka K, Fujiwara Y, Pan C, Esumi S, Saito Y, Bi J, Nakamura Y, Mukunoki A, Takeo T, Nakagata N, Yoshii D, Fukuda R, Nagasaki T, Tanaka R, Komori H, Maeda H, Watanabe H, Tamada K, Komohara Y, Maruyama T.
α1-acid glycoprotein enhances the immunosuppressive and protumor functions of tumor-associated macrophages.
Cancer Res 81:4545-4559, 2021.

21. Matsubara E, Komohara Y, Shinchi Y, Mito R, Fujiwara Y, Ikeda K, Shima T, Shimoda M, Kanai Y, Sakagami T, Suzuki M.
CD163-positive cancer cells are a predictor of a worse clinical course in lung adenocarcinoma.
Pathol Int, in press.

22. Sato R, Imamura K, Semba T, Tomita Y, Saeki S, Ikeda K, Komohara Y, Suzuki M, Sakagami T, Saya H, Arima Y.
TGF-β signaling activated by cancer-associated fibroblasts determines the histological signature of lung adenocarcinoma.
Cancer Res, in press.
ells are a predictor of a worse clinical course in lung adenocarcinoma.
Cancer Res 81: 4751-4765, 2021.

23. Fujiwara Y, Okada S, Uryu K, Maru I, Komohara Y.
The extract of Ilex kudingcha inhibits atherosclerosis in apoE-deficient mice by suppressing cholesterol accumulation in macrophages.
Biosci Biotechnol Biochem 85: 2177-2184, 2021.

24. Hara Y, Yamamura K, Matsumura K, Oda E, Akahoshi S, Yuki H, Tomiguchi J, Motohara T, Miyamoto H, Komohara Y, Beppu T.
Laparoscopic Surgery for a Patient With Multiple Liver Metastases of Unknown Origin Concomitant With Gallbladder Tumor.
In Vivo 35: 2963-2968, 2021.

25. Sakamoto Y, Mima K, Ishimoto T, Ogata Y, Imai K, Miyamoto Y, Akiyama T, Daitoku N, Hiyoshi Y, Iwatsuki M, Baba Y, Iwagami S, Yamashita YI, Yoshida N, Komohara Y, Ogino S, Baba H.
The relationship of Fusobacterium nucleatum with antitumour immunity in colorectal cancer liver metastasis.
Cancer Sci, in press.

26. Yonemitsu K, Miyasato Y, Shiota T, Shinchi Y, Fujiwara Y, Hosaka S, Yamamoto Y, Komohara Y.
Soluble Factors Involved in Cancer Cell-Macrophage Interaction Promote Breast Cancer Growth.
Anticancer Res 41: 4249-4258, 2021.

27. Komohara Y, Anami T, Asano K, Fujiwara Y, Yatsuda J, Kamba T.
Anti-Cancer Immune Reaction and Lymph Node Macrophage; A Review from Human and Animal Studies.
Immuno 1: 223-230, 2021.

28. Matsumoto C, Iwatsuki M, Iwagami S, Morinaga T, Yamashita K, Nakamura K, Eto K, Kurashige J, Baba Y, Miyamoto Y, Yoshida N, Komohara Y, Baba H.
Prophylactic laparoscopic total gastrectomy for gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): the first report in Asia.
Gastric Cancer, in press.

29. Kosaka A, Ishibashi K, Nagato T, Kitamura H, Fujiwara Y, Yasuda S, Nagata M, Harabuchi S, Hayashi R, Yajima Y, Ohara K, Kumai T, Aoki N, Komohara Y, Oikawa K, Harabuchi Y, Kitada M, Kobayashi H, Ohkuri T.
CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes.
J Exp Med 218: e20200792, 2021.

30. Kai K, Komohara Y, Esumi S, Fujiwara Y, Yamamoto T, Uekawa K, Ohta K, Takezaki T, Kuroda J, Shinojima N, Hamasaki T, Mukasa A.
Macrophage/microglia-derived IL-1β induces glioblastoma growth via the STAT3/NF-κB pathway.
Hum Cell, in press.

31. Oda E, Yamamura K, Hara Y, Matsumura K, Akahoshi S, Yuki H, Motohara T, Miyamoto H, Kinoshita K, Matsumura F, Ohnishi K, Komohara Y, Beppu T.
Intrahepatic Cholangiocarcinoma Coexisting With Multiple Bile Duct Adenoma Treated as Liver Metastasis from a Pancreatic Neuroendocrine Tumor.
Anticancer Res 41: 5249-5254, 2021.

32. 菰原義弘.
がん免疫誘導におけるリンパ節洞マクロファージの重要性.
血液内科 83: 63-66, 2021.

33. 大倉航平、菰原義弘、神尾多喜浩.
期食道胃接合部腺癌によりPulmonary tumor thrombotic microangiopathyおよび癌性リンパ管症をきたした1剖検例.
診断病理 38: 181-188, 2021.

ページのトップへ


1. 菰原義弘.  
招待講演
シンポジウム8  がんと免疫病理、最前線 がん免疫微小環境におけるマクロファージの重要性.
第110回 日本病理学会総会 令和3年4月22-24日(東京、京王プラザホテル、ハイブリッド開催)

2. 藤原章雄、松坂幸太朗、潘 程、丸山徹、菰原義弘.
α1-酸性糖タンパク質は腫瘍関連マクロファージに作用することで腫瘍の進展に関与する.
第110回 日本病理学会総会 令和3年4月22-24日(東京、京王プラザホテル、ハイブリッド開催)

3. 西東洋一、藤原章雄、御任玲美、新地祐介、三浦裕司、菰原義弘.
各種がん細胞株のPD-L1発現の特徴分類から考察する臨床がん組織でのPD-L1免疫染色の意義.
第110回 日本病理学会総会 令和3年4月22-24日(東京、京王プラザホテル、ハイブリッド開催)

4. 矢野浩夢、藤原章雄、甲斐恵太郎、菰原義弘.
脂質代謝に着目した脳原発悪性リンパ腫の新たな治療戦略.
第110回 日本病理学会総会 令和3年4月22-24日(東京、京王プラザホテル、ハイブリッド開催)

5. 藤原章雄.
α1-酸性糖タンパク質の腫瘍関連マクロファージへの作用を介した腫瘍進展への寄与.
第17回 日本病理学会カンファレンス 令和3年8月20-21日(主催:新潟大学、web開催)

6. 矢野浩夢.
悪性リンパ腫に対する SR-BI 阻害剤の有効性の検討. 
優秀演題賞
第17回 日本病理学会カンファレンス 令和3年8月20-21日(主催:新潟大学、web開催)
2008 2009 2010 2011 2012 2013 2014 2015 2016 2017
 
2018 2019 2020 2021